"Be anxious for nothing, but in everything by prayer and supplication, with thanksgiving, let your requests be made known to God." (Philippians 4:6)
While even those closest to us may tire of hearing of our desires and needs, God has no such limitation. He is always willing to hear, and even better, to work for your good according to His will. That is why we can bring even our most desperate needs to Him "with thanksgiving". We do not serve a God who only listens; the Creator of the universe is for you. You can bring every need to Him without any anxiety about how He may receive it. Because of this, we can "come boldly to the throne of grace, that we may obtain mercy and find grace to help in time of need" (Hebrews 4:16).